Analytical Platform
The chemical analysis platform is a technological infrastructure dedicated to the advanced characterization of complex matrices derived from fermentation bioprocesses.
With a multidisciplinary team possessing extensive expertise, particularly in the development of methods using various analytical techniques, it offers targeted and non-targeted approaches for the identification, quantification, and structural characterization of substrates, metabolites, and products of interest.
Versatility
and precision
Its instrument suite covers all major chromatographic techniques (LC, IC, GC) coupled with a wide variety of detectors (UV, RI, fluorescence, Corona, MALS, single MS, MS/MS, HRMS), enabling detailed analysis of metabolic pathways, material balances, and limiting factors in fermentation processes.
Area of Specialization and Expertise
The platform plays a key role in understanding and optimizing processes by characterizing metabolic pathways and supporting their optimization, particularly during scale-up phases, through the early detection of limiting, inhibitory, or toxic compounds.
- Targeted or non-targeted analysis of substrates, products, and metabolites
- Quantification of the target compound
- Process optimization by evaluating competing pathways and limiting factors
- Screening of conditions (strain engineering or process engineering)
- Method development and validation
- Conducting material inventories
Equipements
- Liquid, ion, and gas chromatography systems
- UV, fluorescence, RI, Corona, MALS, MS, MS/MS, and HRMS (Orbitrap) detectors
- Elemental analyzers (CHONS and COT/NT)
- MforLab (MagIA Diagnostics) uses wash-free magnetic immunoassay technology
Access and Support
Access to the platform comes with scientific and technical support, including:
- training in the use of certain equipment,
- the provision of experimental tools,
- and tailored follow-up based on the contractual framework (service provision, R&D collaboration, or public-private partnership).
